Metformin tablets for type 2 diabetes mellitus 30pcs

Metformin indications for use: Type 2 diabetes mellitus, especially in obese patients, with ineffective diet therapy and exercise: in adults as monotherapy or in combination with other oral hypoglycemic agents, or with insulin; in children over 10 years of age as monotherapy or in combination with insulin. Directions for use: Take orally during or after meals. The initial dose is 1 tablet (500 mg) once a day in the evening. Adjust the dosage taking into account your sugar level, the maximum dose should not exceed 4 tablets (2000 mg). Metformin contraindications: hypersensitivity to metformin or to any excipient; diabetic ketoacidosis, diabetic precoma, coma; renal failure or impaired renal function (creatinine clearance (CC) less than 60 ml/min); acute conditions that occur with a risk of developing renal dysfunction: dehydration (with diarrhea, vomiting), severe infectious diseases, shock; clinically pronounced manifestations of acute or chronic diseases that can lead to the development of tissue hypoxia (including cardiac or respiratory failure, acute myocardial infarction); extensive surgical operations and injuries, when insulin therapy is indicated; liver failure, liver dysfunction; chronic alcoholism, acute alcohol poisoning; pregnancy; lactic acidosis (including history); use within less than 48 hours before and within 48 hours after radioisotope or x-ray studies with the introduction of an iodine-containing contrast agent (see section “Interaction with other drugs”); following a low-calorie diet (less than 1000 kcal/day); children under 10 years of age. Use the drug with caution in people over 60 years of age who perform heavy physical work, which is associated with an increased risk of developing lactic acidosis; during breastfeeding. Use during pregnancy and breastfeeding Limited evidence suggests that taking metformin in pregnant women does not increase the risk of birth defects in children. When planning pregnancy, as well as in the event of pregnancy while taking metformin, the drug should be discontinued and insulin therapy should be prescribed. It is necessary to maintain the glucose level in the blood plasma at a level closest to normal to reduce the risk of fetal malformations. Metformin is excreted in breast milk. No side effects were observed in breastfeeding newborns while taking metformin. However, due to limited data, the use of the drug during breastfeeding is not recommended. The decision to stop breastfeeding should be made taking into account the benefits of breastfeeding and the potential risk of side effects for the baby.